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A second human patient has received a genetically altered pig heart as he battles the ravages of end-stage heart disease.

The 58-year-old man, Lawrence Faucette, received the pig organ at the University of Maryland Medical Center in Baltimore.

The medical team was the same one that performed the first pig transplant with another patient in January 2022.

“We are once again o...

Receiving an organ transplant can be a nerve-wracking, if lifesaving, affair, said Dr. Joaquin Brieva, a kidney transplant recipient.

“Within two days of my transplant, my kidney function was back to normal, but then you worry about the possibility of ...

For the first time ever, a solid humanized organ has been grown from scratch in an animal — a first step in a process that could potentially solve organ shortages and save countless lives.

Chinese researchers grew partially human early-stage kidneys inside embryonic pigs, using a variety of genetic engineering techniques, a new report reveals.

“This study demonstrates proof-of-p...

A new study in non-human primates shows potential for using a manmade monoclonal antibody to help prevent organ rejection after a transplant.

The antibody was successful in promoting graft survival after kidney and pancreatic islet cell transplantations, according to the research.

This clears a path for this new monoclonal antibody to move forward in human clinical trials, the rese...

Valance Sams Sr. believes that he has experienced "a miracle."

Sams, now 46, underwent a triple organ transplant in the spring of 2023, making him one of fewer than 50 people in the United States to ever receive three new organs via transplantation.

He received a new heart, kidney and liver during a 20-hour operation at Cedars-Sinai Medical Center in Los Angeles that involved around...

Genetically engineered pig kidneys are nearing the point where they could provide a government-approved, sustainable supply of organs for sick humans awaiting a transplant, a pair of new studies argue.

A lightly modified pig kidney has continued to function more than a month in a brain-dead human donor kept alive on a ventilator, according to an ongoing study conducted at NYU Langone Heal...

Dennis Deer woke from surgery in utter disbelief that he was breathing normally.

He'd been on supplemental oxygen for two years, and “I didn't know what it was like not to have something on my face,” said Deer, 51, a Chicago-area politician and psychologist.

“I immediately said, 'Where is my oxygen?' And my wife said to me, ‘Well, you don't need the oxygen anymore,'" Deer re...

Many transplant centers routinely practice “list-diving,” when the top candidate among potential organ recipients is skipped in favor of someone further down the list, new research shows.

The top candidate is ranked that way based on an objective algorithm using age, waiting time and other factors, while choosing someone else happens with little oversight or transparency. And that may...

A new transplant method that "reanimates" donor hearts appears safe and effective, a new clinical trial has found — in an advance that could substantially expand the supply of donor hearts available in the United States.

The trial tested an approach that allows doctors to transplant hearts from donors who have succumbed to "circulatory death" — meaning the heart has stopped beating. T...

Storing donor lungs at cool — but not near freezing — temperatures can markedly increase the length of time the organs can live outside the human body, a new study suggests.

Lungs stored at 50 degrees Fahrenheit remain healthy and viable for transplant up to four times longer than those stored at the current standard temperature of 39 degrees, according to new clinical trial results.<...

Far more people need an organ transplant than there are organs available.

It doesn't have to be that way.

Dr. Johnny Hong, chief of transplantation at Penn State Health's Milton S. Hershey Medical Center in Hershey, explored some of the myths about organ donation.

“We have an organ sh...

A single nonprofit has what amounts to a monopoly over all organ transplants performed in the United States, but the federal government said Wednesday that it plans to change that.

The Health Resources and Services Administration (HRSA), which has contracted with the United Network for Organ Sharing (UNOS) to run the Organ Procurement and Transplantation Network for 37 years, announced ...

Retired nurse Tannaz Ameli was diagnosed with stage 4 lung cancer last winter. When chemotherapy failed, her doctors recommended hospice care.

But Ameli, of Minneapolis, had other ideas. She and her husband sought out a pioneering medical team at Northwestern Medicine in Chicago. Today, she is a survivor of a double-lung transplant -- just the second this team of specialists has succ...

Doctors have discovered a way to extend the short shelf life of donor hearts, which could hopefully make more of the organs available to desperate recipients.

Valproic acid (Depakote), which is approved to treat seizures, boosts production of an enzyme that increases the length of time donated hearts can be stored and transported.

The drug also could improve the hearts' function aft...

Massachusetts legislators have proposed a bill that would allow prison inmates to donate their organs or bone marrow as a way to trim the length of their sentence.

While some experts wonder about the ethics of such a law and whether it would even be allowed under federal law, a Democratic sponsor of the bill,

A new way of allocating donor lungs that eliminates geographical restrictions could save more lives, new research suggests.

In early 2023, the current U.S. system, which looks for compatible candidates within a fixed radius, will be replaced by the Composite Allocation Score. The new score will prioritize a candidate's medical needs.

“The importance of removing the geographical ba...

Once a year, giant motorcycle rallies ride into places like Daytona Beach, Fla., and Sturgis, S.D., bringing hundreds of thousands of people, an economic boost -- and a wave of crash-related deaths.

That means more organs available for donation and the need to be prepared, according to a