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02 Sep

With 'Chemical Imbalance’ Theory in Doubt, What’s Next for Depression Care?

HealthDay’s Mabel Jong will be joined by Dr. Joanna Moncrieff, professor of psychiatry at University College London, and Dr. Srijan Sen, professor of depression and neurosciences at the University of Michigan. Moncrieff and Sen will discuss the future of depression treatment -- within the context of a large systematic review, co-authored by Moncrieff, that found no evidence to back up the “chemical imbalance” theory linking depression and low serotonin levels.

29 Aug

Popular Painkillers May Pose Heart Risk for Patients with Type 2 Diabetes, Study Finds

Older adults with type 2 diabetes face an increased risk of heart failure after using certain NSAIDs, researchers say.

Health News Results - 170

Popular Painkillers May Pose Heart Risk for Patients with Type 2 Diabetes, Study Finds

  • By HealthDayTV HealthDay Reporter
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  • August 29, 2022
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  • Full Page
  • Magic Mushroom Hallucinogen May Treat Problem Drinking

    Jon Kostas, a lifelong resident of New York City, started bar-hopping at age 13. At the height of his alcoholism, he was consuming as many as 30 drinks a night.

    Desperate for a way out, Kostas, 32, turned to a new therapy: psilocybin -- the psychedelic compound found in so-cal...

    LSD Is Making a Comeback Among Young Americans

    If you think hallucinogens like LSD are a thing of the past, think again.

    New research estimates that the use of mind-altering LSD rose from less than 1% in 2002 to 4% in 2019 among people aged 18 to 25. And, overall, 5.5 million Americans used some kind of hallucinogen in 2019.

    "According to our results, hallucin...

    Use of Pot, Hallucinogens Soaring Among Young Americans

    Marijuana and hallucinogen use are at an all-time high among young adults, U.S. health officials reported Monday.

    Compared to five or 10 years ago, the use of these drugs over the past year has risen significantly among 19- to 30-year-olds, according to the Monitoring the Future panel study. The new dat...

    Want That Pill to Work Fast? Your Body Position Matters

    If you need to take a pill, you might want to take it lying down -- on your right side, that is.

    Researchers studying how body positioning affects the absorption of pills found that one taken when a person was lying on the right side speeded pills to the deepest part of the stomach. That pill could then dissolve 2.3 times faster than if the person was upright.

    "We were very surprise...

    Here's How New Federal Legislation Might Cut Your Drug Costs

    The Inflation Reduction Act is expected to bring out-of-pocket drug costs down for many U.S. seniors, but most of its benefits aren't immediate.

    Under the law, Medicare will now be allowed to negotiate the cost of some drugs. That should eventually bring down out-of-pocket costs for seniors with Medicare Part D prescription drug plans, according to John Clark, a clinical associate profess...

    Methadone ODs Didn't Rise in Pandemic, Supporting Use as At-Home Treatment

    Giving more patients at-home access to the opioid addiction treatment drug methadone during the COVID pandemic did not lead to more overdose deaths, a nationwide study shows.

    The research, which covered the period from January 2019 to August 2021, found that the push to let more patients take home doses rather than visit a clinic daily did not increase harm among users.

    "Treatment ...

    Odds for Emergency Room Visits Rise With Pot Use

    Toking up increases your risk of landing in the hospital, a new study reports.

    Recreational marijuana use was associated with 22% greater odds of needing to visit an emergency room or be hospitalized, Canadian researchers found.

    The study showed physical injuries, lung ailments and ga...

    Intentional Overdoses Rise Among U.S. Kids, Teens

    A growing number of U.S. kids are attempting suicide by medication overdose - with the biggest increase seen among preteens, a recent study shows.

    Researchers found that between 2015 and 2020, there was a 27% increase in overdose suicide or attempted suicide among U.S. children and teenagers. While teens accounted for most of those incidents, it was 10- to 12-year-olds who showed the bigg...

    How the 'Magic Mushroom' Drug May Tweak the Brain to Ease Depression

    Psilocybin - the active component in "magic mushrooms" - may help rewire the brains of people with depression.

    Psychedelics including psilocybin have shown promise in treating many mental health disorders in recent years, and a new study is among the first to begin to unravel precisely how they work.

    "T...

    Ketamine May Be Emergency Deterrent for People at Risk of Suicide

    A new clinical trial strengthens the case that ketamine -- once famous as a club drug -- can rapidly ease suicidal thoughts.

    Researchers found that among 156 adults hospitalized for severe suicidal thoughts, those given two doses of ketamine often saw those disturbing ideas go away within a few days.

    By day three, 63% were in full remission, compared to just under 32% of patients gi...

    People High on Pot Used a Driving Simulator. Here's What Happened

    You smoked a joint an hour and a half ago. Now it's worn off enough that you feel fine to get behind the wheel.

    But you're fooling yourself, a new study says. You're likely about to drive under the influence of weed, endangering yourself and others.

    Marijuana ...

    Common Gout Drug Is Safe in Patients With Kidney Issues

    Allopurinol, a frequently used gout medication, does not appear to drive up the risk for dying among gout patients who also struggle with chronic kidney disease, new research shows.

    The finding is based on an analysis of two decades worth of British health records. And it may put to rest recent concerns regarding a well-known drug that both gout patients and kidney disease patients have u...

    More Folks Drive High When Pot Made Legal: Study

    Here's more evidence that marijuana may make driving more dangerous: As pot has been legalized in more countries and states, a greater number of people are driving intoxicated by the drug and crashing, researchers report.

    THC, the active ingredient in cannabis, has been detected in twice as many injured Canadian drivers since 2018, when

  • Steven Reinberg HealthDay Reporter
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  • January 13, 2022
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  • Opioid Misuse Keeps Rising Among Older Americans

    The opioid addict you know might not be the college kid who has always dabbled in alcohol and drugs.

    It could be your grandparent.

    Opioid misuse doesn't discriminate by age -- and rates are rising steadily among adults aged 55 and up, new research shows.

    "You can still use recrea...

    Marijuana Can Really Mess With Your Sleep, Study Suggests

    Many folks turn to pot to help them relax and get a good night's sleep, but new research finds the practice may do the exact opposite.

    "I think [the results] were somewhat surprising because, in our mind, anecdotally cannabis seems to help with sleep, but … the evidence to support that notion is just not there yet," said senior study author Dr. Karim Ladha. He is an anesthesiologist and...

    'Magic Mushroom' Drug Edges Toward Mainstream Therapy

    Tony Head was depressed and fearing death from stage 4 prostate cancer when, as part of a supervised scientific trial, he took a large dose of the psychedelic agent in "magic mushrooms," psilocybin.

    Head donned a mask and headphones to shut out the world around him, and had an experience that changed the course of his life.

    "At some point in that time I felt like a higher power or s...

    Wearable Device Spots, Reverses Opioid Overdoses

    A wearable device that could inject a lifesaving antidote for an opioid overdose might be on the horizon.

    A new study shows that the device, worn on the stomach like an insulin pump, can detect when someone stops breathing from an overdose and inject the drug naloxone to restore breathing.

    "Fatal drug overdoses in the United States are at an all-time high, and opioid overdoses accou...

    Addictive Opioid Painkillers Might Not Be Needed After Knee Surgery

    Addictive opioid painkillers aren't the only option for patients seeking relief following anterior cruciate ligament (ACL) knee reconstruction, researchers say.

    As the United States wrestles with skyrocketing rates of opioid abuse and drug overdose deaths, the findings may come as good news.

    After ACL surgery, Advil and other nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminop...

    Over 100,000 Americans Died From Drug Overdoses in One Year: Report

    New government data confirms what many have suspected: The pandemic has prompted a record number of drug overdose deaths, with more than 100,000 Americans succumbing to addiction as COVID-19 raged across the country.

    That figure is almost 30% higher than the previous year, when 78,000 overdose deaths were reported, according to provisional figures from the U.S. Centers for Disease Control...

    Medicare Could Negotiate Drug Prices Under Democrat Proposal

    A measure designed to lower prescription drug costs for seniors has been added to President Joe Biden's social safety net and climate change bill that Democratic leaders hope to bring to a House vote this week.

    For the first time, the measure would enable the federal government to negotiate prices for medications covered by Medicare, The New York Times reported.

    Under the proposal, ...

    Number of Teens Who Vape Marijuana Doubled in 7 Years

    Teenagers have followed the vaping trend into marijuana use, with recent studies chronicling a boom in pot vaping among adolescents in the United States and Canada, researchers report.

    The percentage of teens who've experimented with vaped pot has more than doubled in recent years, and vaping among frequent marijuana users has quadrupled, according to the study.

    Currently about 1 in...

    Scientists Develop Quick Test for Marijuana Use

    Researchers may be one step closer to developing the equivalent of a Breathalyzer for detecting marijuana use.

    In an early study, scientists found that their rapid test was able to reliably detect THC in people's saliva in under 5 minutes. THC, short for tetrahydrocannabinol, is the active ingredient in marijuana.

    Right now, the "gold standard" for detecting marijuana use is to meas...

    DEA Warns of Fentanyl in Counterfeit Opioid Pills

    People buying pills that look like prescription opioid painkillers or stimulants who are not buying them from a licensed pharmacy may be buying a lethal drug, the U.S. Drug Enforcement Administration warned this week.

    This was the first public safety alert the DEA has issued in six years, CNN reported.

    Many of these counterfeit pills are laced with fentanyl and methamphetam...

    Pot Use by Pregnant Women Rose During Pandemic: Study

    Marijuana use by mothers-to-be may have increased by as much as one-quarter during the pandemic, a new study suggests.

    Researchers found a substantial increase in the number of women in Northern California using pot early in their pregnancies after the pandemic emerged compared to the previous year.

    "Our previous research has shown that the prevalence and frequency of prenatal canna...

    Opioid Use Disorder Is as Deadly as Heart Attack: Study

    Hospitalized opioid addicts die at a rate similar to people who have a heart attack after leaving the hospital.

    Nearly 8% of patients addicted to opioids died within 12 months of hospital discharge, according to researchers from Oregon Health & Science University (OHSU).

    "We need systems that can address comprehensive needs of people with substance use disorder and serious medical i...

    Half of Adults With ADHD Have Struggled With Alcohol, Drug Use

    Fully half of all young adults with attention deficit hyperactivity disorder (ADHD) may also battle alcohol or drug abuse.

    And folks with ADHD who have a history of depression or anxiety are particularly vulnerable to substance abuse problems, a new study showed.

    "People with ADHD may be self-medicating with drugs or alcohol to keep their depression under control, and of course, th...

    Fatal ODs From Illicit Tranquilizers Jumped 6-Fold During Pandemic

    Overdose deaths linked to illicit "designer" benzodiazepines have surged in the United States, as underground labs crank out new synthetic variations on prescription tranquilizers like Valium, Xanax and Ativan.

    Overdose deaths involving illicit benzos increased more than sixfold (520%) between 2019 and 2020, rising from 51 to 316, according to data from 32 states and the District of Colum...

    Rising Number of U.S. Cardiac Arrests Tied to Opioid Abuse

    There's been a sharp rise in opioid-related cardiac arrests in the United States and they now equal those associated with other prime causes, a new study finds.

    Of more than 1.4 million cardiac arrest hospitalizations nationwide between 2012 and 2018, more than 43,000 (3.1%) occurred in opioid users, and there was a significant increase in opioid-associated cardiac arrest over the seven-y...

    How Your Medicines Make Their Way Into Rivers, Lakes and Bays

    Leaky sewer pipes are to blame for large amounts of human medicines getting into rivers, lakes and other bodies of water, a new study reveals.

    Researchers found that tens of thousands of doses of drugs get into Chesapeake Bay in Maryland every year due to seeping sewer pipes.

    "Pharmaceuticals enter freshwaters through multiple pathways, including effluent from wastewater treatment a...

    Two PrEP Meds Work Equally Well; One Is Much Cheaper

    The two HIV prevention drugs available in the United States are equally safe and effective, and the biggest difference between them is price, a new study contends.

    However, a sizable minority of patients have switched from the older and cheaper "preexposure prophylaxis" (PrEP) formulation to the newer and much pricier one. In many cases that switch might not have been warranted, the resea...

    Could Heavy Marijuana Use Be Driving Rise in Schizophrenia Cases?

    There's been a sharp rise in schizophrenia cases linked with marijuana use since the mid-1990s, a new Danish study finds.

    Prior research has suggested that marijuana -- particularly very heavy use -- is associated with an increased risk of schizophrenia. Although strict cause-and-effect can't be proven by the new study, many experts believe that heavy pot use might work in conjuncti...

    U.S. Drug Overdose Deaths Jumped Nearly 30% During Pandemic

    As America went into lockdown and treatment centers closed their doors, drug overdose deaths in the United States jumped by nearly a third last year, new data show.

    The estimated 93,331 drug overdose deaths recorded during 2020 are a sharp increase -- a 29.4% rise -- over the 72,151 deaths estimated in 2019, according to preliminary data from the National Center for Health Statistics (NC...

    Is Medicare Overspending? Costco Prices Much Less for Generic Drugs

    Can Costco beat Medicare Part D when it comes to prescription drug prices?

    Apparently so, claims a new study that found that roughly half of generic medications were cheaper when purchased from the discount retailer than from the government program.

    The researchers compared the prices paid by Medicare Part D plans (including patient out-of-pocket payments) for 184 generic prescripti...

    Pot Use May Change the Teenage Brain, MRIs Show

    Smoking pot appears to affect teens' brain development, altering it in ways that could diminish their reasoning, decision-making and memory skills as they age, a new study reports.

    Brain scans of about 800 teenagers found that those who started smoking pot tended to have increased thinning of the cerebral cortex -- the outer layer of the brain responsible for thought, perception and langu...

    Doctors May Be Overprescribing Opioids After Surgeries

    Many patients who are prescribed opioids after surgery could get the same level of pain relief with non-opioid alternatives such as ibuprofen or acetaminophen without the risk of addiction, researchers say.

    "Opioids have been a routine part of postsurgical pain care for decades, but the risk that they could lead to persistent use has been clearly documented," said lead author Dr. Ryan How...

    Newly Approved Drug Fights Lung Cancer Tied to Certain Genes

    A newly approved lung cancer drug shows promise in improving survival in patients whose tumors carry a common and tough-to-treat genetic mutation, researchers say.

    Sotorasib - brand name Lumakras - was approved May 28 by the U.S. Food and Drug Administration as a targeted therapy for non-small cell lung cancer patients with tumors that express the G12C mutation in the KRAS gene, ...

    There's Been a Shift in Who's Funding Alzheimer's Research

    The U.S. government and nonprofits are replacing drug companies as the main drivers of Alzheimer's disease research, two new studies show.

    The findings are from an analysis of national data by Jeffrey Cummings, a research professor at the University of Nevada, Las Vegas School of Integrated Health Sciences.

    In one study, his team found that the number of Alzheimer's clinical trials ...

    Reviews Find No Evidence Weight-Loss Supplements Work

    You're getting no real benefit from taking weight-loss supplements like garcinia cambogia, green tea extract, glucomannan, conjugated linoleic acid or chitosan, two new reviews show.

    Most of the clinical trials studied didn't show these supplements producing any weight loss among users, the researchers said. In the rare cases where people did lose weight, they didn't drop enough pounds to...

    When Drug Companies Raise Prices, Patients' Out-of-Pocket Costs Rise

    When prescription drug "list" prices go up, patients often take a hit in the wallet, a new study shows.

    Researchers found that while some people are buffered against drug price hikes by their health insurance plan, many are not.

    Those in plans that require co-insurance or a deductible for prescriptions typically watch their out-of-pocket expenses rise, according to the study.

    Many Older Americans Aren't Telling Their Doctors They Use Pot

    Aging potheads are now past 50 and still puffing away, but new research shows that many don't disclose this to their doctors.

    Folks who use marijuana for medical reasons are more likely to tell their doctors about it than recreational users. Still, just a fraction of medical marijuana users opened up about their use, the study found.

    "Older adults may worry about how doctors would r...

    Who Is Using Herbal Kratom?

    Herbal kratom is used by less than 1% of the U.S. population, but the rate is much higher among those who misuse opioid painkillers, a new study finds.

    Kratom is used to manage pain and opioid withdrawal. However, it carries the risk of addiction and harmful side effects, which has led the U.S. Food and Drug Administration and the Drug Enforcement Administration to identify kratom as a "d...

    1 in 5 U.S. Pharmacies Blocks Access to Key Opioid Addiction Treatment

    The Biden administration has eased guidelines for prescribing a crucial addiction treatment drug, just as a new study reveals one in five U.S. pharmacies refuses to dispense the medication, called buprenorphine.

    "Buprenorphine is a vital, lifesaving medication for people with opioid use disorder, but improving access has been a problem for a variety of reasons," said the study's senior au...

    'Magic Mushroom' Hallucinogen as Good as Antidepressants: Study

    The magic ingredient in "magic mushrooms" may be at least as effective as standard medication for depression, an early clinical trial suggests.

    The study of 59 patients with major depression tested the antidepressant escitalopram (Lexapro) against psilocybin, which is the psychedelic substance in hallucinogenic mushrooms.

    Over six weeks, it appeared that just two doses of psilocybi...

    CBD or THC? Cannabis Product Labels Often Mislead, Study Finds

    Patients, beware: You might not be able to trust the label on that medical marijuana product you just brought home.

    Levels of the two active ingredients in medicinal cannabis -- THC and CBD -- can vary widely from those claimed by distributors, a new study warns.

    "People are buying products they think are THC-free but, in fact, contain a significant amount of THC," said researcher J...

    Forget the 'Lazy Stoner': Marijuana Users Don't Exercise Any Less

    The stereotypical image of pot smokers has long been one of "stoners" parked on the couch, surrounded by snacks and glued to the television, but a new study dispels that notion.

    Instead, people who use marijuana may exercise just as much as other people do, and perhaps even a little more, researchers report.

    Considering how important regular exercise is to one's overall health, the ...

    Legalized Pot Tied to Rise in Young Men's Suicide Attempts

    States that make marijuana a readily available retail item might see an increase in self-harm among younger men, a new study suggests.

    Researchers found a correlation between U.S. states' shifting marijuana policies and rates of self-harm among men younger than 40. Those rates -- which include suicide attempts and non-suicidal behaviors like cutting -- increased in states that legalized, ...

    Certain HIV Meds Have Patients Packing on Pounds

    A commonly prescribed component of the life-saving antiretroviral drug cocktails used to treat HIV may trigger weight gain, new research warns.

    The concern stems from tracking patients taking antiretroviral therapy (ART). Since the mid-1990s, the therapy has relied on various drug combinations to essentially outwit HIV, controlling viral loads and turning a once-deadly infection into a ma...

    Opioid Addiction Relapse May Be Different for Men, Women

    Who is more likely to relapse after opioid addiction treatment -- women or men?

    A new study that followed 1,100 recovering opioid users reveals that their risks are different.

    The researchers followed the men and women for one year after treatment at more than 100 substance-use treatment facilities across the United States. During that time, 55% of the women and 51.5% of the men use...

    Choice of Brand-Name Drug Over Generics Costs Medicare Nearly $2 Billion Annually

    Wider use of prescription generic drugs could save Medicare nearly $2 billion a year, researchers say.

    The new analysis of Medicare Part D prescription drug claims for 2017 used a random 20% of beneficiaries, 224 drugs with one or more generic substitutes and at least 1,000 claims.

    Medicare Part D accounts for roughly one-third of all prescription drug spending in the United States....

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